The relation between isolated micropenis in childhood with CAG and GGN repeat polymorphisms in the androgen receptor gene

Tuğ E., Ergun S. G., Ergün M. A., Dilek F. N., Percin E. F.

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.48, no.2, pp.430-434, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 48 Issue: 2
  • Publication Date: 2018
  • Doi Number: 10.3906/sag-1710-183
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.430-434
  • Gazi University Affiliated: Yes

Abstract

Background/aim: In micropenis cases accompanied by external genital abnormalities such as hypospadias and cryptorchidism, infertility and spermatogenic failures have been reported to correlate with androgen receptor (AR) gene CAG and GGN repeat polymorphisms. While there is one study on isolated micropenis and CAG repeats, no study related to GGN repeats has been reported. We investigated the relation between CAG and GGN repeats in the AR gene with development of penis length in boys with isolated micropenis.