A rare case of primary inoculation tuberculosis seen after varicella


Polat M., Kara S. S., TAPISIZ A., TEZER H., Ogut B., Uluoglu O.

TURKISH JOURNAL OF PEDIATRICS, vol.57, no.2, pp.192-194, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 57 Issue: 2
  • Publication Date: 2015
  • Journal Name: TURKISH JOURNAL OF PEDIATRICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.192-194
  • Keywords: Mycobacterium tuberculosis, primary inoculation tuberculosis, varicella, CUTANEOUS TUBERCULOSIS, ZOSTER-VIRUS, EXPRESSION, INFECTION, COMPLEX, CELLS
  • Gazi University Affiliated: Yes

Abstract

Primary inoculation tuberculosis (TB) is a rare form of cutaneous TB resulting from direct introduction of Mycobacterium tuberculosis into the skin or mucosa of a previously uninfected, nonimmune person. We herein report the first case, to our knowledge, of primary inoculation TB to be seen after varicella; this case explains the possible mechanism of varicella-zoster virus-mediated transient cellular immune suppression that predisposed the patient to cutaneous TB. In this case, we believe that varicella-zoster virus (VZV) infection predisposed the patient to primary inoculation TB by leading to direct inoculation of tuberculosis bacilli through vesicles or by suppressing cellular immunity.