I-123-mIBG myocardial imaging for assessment of risk for a major cardiac event in heart failure patients: insights from a retrospective European multicenter study

Agostini D., Verberne H. J., Burchert W., Knuuti J., Povinec P., Sambuceti G., ...Daha Fazla

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, cilt.35, sa.3, ss.535-546, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 35 Sayı: 3
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1007/s00259-007-0639-3
  • Dergi Adı: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.535-546
  • Anahtar Kelimeler: cardiology, mIBG, scintigraphy, nuclear imaging, prognosis, IMPLANTABLE CARDIOVERTER-DEFIBRILLATORS, LEFT-VENTRICULAR DYSFUNCTION, DILATED CARDIOMYOPATHY, SYMPATHETIC INNERVATION, PROGNOSTIC VALUE, METAIODOBENZYLGUANIDINE UPTAKE, EJECTION FRACTION, RATE-VARIABILITY, DISEASE, SCINTIGRAPHY
  • Gazi Üniversitesi Adresli: Evet

Özet

Purpose Single-center experiences have shown that myocardial meta-iodobenzylguanidine (mIBG) uptake has prognostic value in heart failure (HF) patients. To verify these observations using a rigorous clinical trial methodology, a retrospective review and prospective quantitative reanalysis was performed on a series of cardiac I-123-mIBG scans acquired during a 10-year period at six centers in Europe.