Protective effects of Nigella sativa oil against carboplatin-induced liver damage in rats

Erisgin Z., ATASEVER M., Cetinkaya K., AKARCA DİZAKAR S. Ö., ÖMEROĞLU S., ŞAHİN H.

BIOMEDICINE & PHARMACOTHERAPY, vol.110, pp.742-747, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 110
  • Publication Date: 2019
  • Doi Number: 10.1016/j.biopha.2018.12.037
  • Journal Name: BIOMEDICINE & PHARMACOTHERAPY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.742-747
  • Keywords: Apoptosis, Carboplatin, Nigella sativa, Gas chromatography, Liver, Rat, INDUCED HEPATOTOXICITY, THYMOQUINONE, INTRAPERITONEAL, CHEMOTHERAPY, TOXICITY, INJURY, STRESS, MODEL
  • Gazi University Affiliated: Yes

Abstract

Objective: This study aimed to investigate the protective effects of nigella saliva oil (NSO) against liver damage due to intraperitoneal (i.p.) usage of carboplatin which is commonly used as a chemotherapeutic agent.