The relationship between vascular endothelial growth factor (VEGF) and microalbuminuria in patients with essential hypertension

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Ebinc F. A., Haksun E., Ulver D. B., Koc E., ERTEN Y., ALTOK K., ...Daha Fazla

INTERNAL MEDICINE, cilt.47, sa.17, ss.1511-1516, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 17
  • Basım Tarihi: 2008
  • Doi Numarası: 10.2169/internalmedicine.47.1122
  • Dergi Adı: INTERNAL MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1511-1516
  • Gazi Üniversitesi Adresli: Evet

Özet

Objective The existence of microalbuminuria (MAU) in patients with essential hypertension is a strong indicator of microvascular damage. Although endothelial dysfunction and increased vascular permeability both have a role in the development of MAU, its ethiopathogenesis in hypertensive patients is not yet clearly understood. Vascular endothelial growth factor (VEGF) is the most important regulator of pathological or physiological angiogenesis and it additionally leads to increased vascular permeability. This study aims to assess the relationship of serum VEGF levels to MAU in non-complicated, newly-diagnosed essential hypertensive patients (EHs).