Akademik Veri Yönetim Sistemi
Turk Beyin Damar Hastaliklar Dergisi, cilt.12, sa.1, ss.11-14, 2006 (Scopus)
Objective: While many physiological actions occur in accordance with circadian rhythm in the organism, many studies showed the rhythmicity for some diseases. In this study, we investigated the relation between cerebrovascular disease and circadian, circannual rhythm as time factor for the onset of the disease. Material and methods: Four hundred-sixty five patients admitted with cerebrovascular disease were included this study. All patients were asked for in which hours of the day the symptoms started (information was obtained from the patient but if not possible from the family of the patient). To investigate the distribution of circadian rhythm, a day was divided into 4 as 6 hours of period and to investigate the distribution of circannual rhythm, a year was divided into 4 as 3 months of period. Results: When all patients were evaluated according to circadian distribution, the onset of the disease was between 00.01-06.00 in 85 (18,3%) patients, between 06.01-12.00 in 139 (29,9%) patients, between 12.01-18.00 in 143 (30,8%) patients and between 18.01-24.00 in 98 (21,1%) patients. This was not statistically different (p>0.05). When we investigated the relation with the seasons, the disease was occurred in the summer in 111 (22,9%) patients, in the autumn in 142 (30,5%) patients, in the winter in 150 (32,3%) patients and in the spring in 62 (13,3%) patients. This was not statistically different (p>0.05). Similar association was also not observed between hemorrhage and infarctus. Conclusion:We found that there was no relation between cerebrovascular disease and circadian rhythm and as an effect of the seasons, there was no relation between circannual rhythm and cerebrovasular events. It can be considered that cerebrovascular disease may not be associated with the time of the disease onset.