Prognostic Factors and Long-Term Outcome in 52 Turkish Children With Hemophagocytic Lymphohistiocytosis.

Kaya, ZÜHRE; Bay, Ali; Albayrak, Meryem; Kocak, Ulker; Yenicesu, Idil; Gursel, Turkiz

doi:10.1097/pcc.0000000000000449

Prognostic Factors and Long-Term Outcome in 52 Turkish Children With Hemophagocytic Lymphohistiocytosis.

Kaya Z., Bay A., Albayrak M., Kocak U., Yenicesu I., Gursel T.

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, cilt.16, sa.6, 2015 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 16 Sayı: 6
Basım Tarihi: 2015
Doi Numarası: 10.1097/pcc.0000000000000449
Dergi Adı: Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Anahtar Kelimeler: children, hemophagocytic syndrome, prognosis, STEM-CELL TRANSPLANTATION, DISSEMINATED INTRAVASCULAR COAGULATION, LYSINURIC PROTEIN INTOLERANCE, RISK-FACTORS, MUTATIONS, PRESENTATIONS, SYNTAXIN-11, GUIDELINES, PHENOTYPES, INFECTION
Gazi Üniversitesi Adresli: Evet

Özet

Objectives: Hemophagocytic lymphohistiocytosis is a syndrome of pathologic immune activation that shares similar clinical and laboratory phenotypes with severe sepsis. Recent studies led to better recognition of hemophagocytic lymphohistiocytosis by clinicians, but no consensus exists on the criteria for high-risk patients.