Akademik Veri Yönetim Sistemi
Annals of Medical Research, cilt.27, sa.3, ss.895-902, 2020 (Hakemli Dergi)
Aim: Hemodialysis patients should have an access to a vessel. Thrombosis is responsible for 80-85% of fistula losses. Mean PlateletVolume (MPV) is routinely measured in complete blood count and shows the average volume of circulating platelets. In our study, weaimed to investigate whether MPV values may be used as a cheap and noninvasive marker in the early diagnosis and intervention ofarteriovenous fistula (AVF) thrombosis.Material and Methods: This retrospective study included 48 patients having one or more episodes of late fistula thrombosis at thehemodialysis unit and 47 patients without history of AVF thrombosis.Results: Demographic and laboratory characteristics were used to compare between groups and no significant difference was found(p> 0.05). On the other hand, significant difference was reported (p=0.001) by the comparison of two groups. Logistic regressionanalysis, revealed that MPV was an independent risk predictor for the development of AVF thrombosis (p <0.05).Conclusion: AVF dysfunction leads to a significant cost and frequent hospitalization of the patient. Previously, MPV was stated tobe a risk factor for arterial and venous thrombosis. This study showed that MPV values may be used in hemodialysis patients asa predictor of thrombosis. Further prospective and retrospective studies should be conducted in order to verify the finding of thisstudy.