Effects of Vascular Endothelial Growth Factor on Ischemic Spinal Cord Injury Caused by Aortic Cross-Clamping in Rabbits

Oyar E. O., Kardes O., Korkmaz A., ÖMEROĞLU S.

JOURNAL OF SURGICAL RESEARCH, vol.151, no.1, pp.94-99, 2009 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 151 Issue: 1
  • Publication Date: 2009
  • Doi Number: 10.1016/j.jss.2008.01.006
  • Journal Name: JOURNAL OF SURGICAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.94-99
  • Keywords: VEGF, ischemia-reperfusion, oxidative stress, spinal cord, BRAIN, VEGF, ANGIOGENESIS, GLUTATHIONE, EXPRESSION, HYPOXIA, DAMAGE, GENES, RAT
  • Gazi University Affiliated: Yes

Abstract

Background. Spinal cord injury remains a devastating complication of thoracic and thoracoabdominal aortic operations. We aim to investigate neuro-protective role of vascular endothelial growth factor (VEGF) administered to rabbits after occlusion against ischemiareperfusion (I/R) injury.