Evaluation of intraprostatic metabolism of 1,25-dihydroxyvitamin D-3 (calcitriol) using a microdialysis technique

Konety, BR; Somogyi, G; Atan, ALİ; Muindi, J; Chancellor, MB; Getzenberg, RH

doi:10.1016/s0090-4295(01)01652-1

Evaluation of intraprostatic metabolism of 1,25-dihydroxyvitamin D-3 (calcitriol) using a microdialysis technique

Konety B., Somogyi G., Atan A., Muindi J., Chancellor M., Getzenberg R.

UROLOGY, cilt.59, sa.6, ss.947-952, 2002 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 59 Sayı: 6
Basım Tarihi: 2002
Doi Numarası: 10.1016/s0090-4295(01)01652-1
Dergi Adı: UROLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.947-952
Gazi Üniversitesi Adresli: Hayır

Özet

Objectives. 1,25-dihydroxyvitamin D-3 (calcitriol) inhibits prostate cancer growth in vitro and in vivo. We used a prostate microdialysis technique to better understand the intraprostatic pharmacokinetics of calcitriol, which in turn would facilitate planning for systemic calcitriol therapy in patients with prostate cancer.