Vincristine-induced peripheral neuropathy and urinary bladder paralysis in a child with rhabdomyosarcoma

Citak E. C., Oguz A., KARADENİZ C., KARAOĞLAN B., TAN M. Ö., Okur V., ...More

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, vol.30, no.1, pp.61-62, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 1
  • Publication Date: 2008
  • Doi Number: 10.1097/mph.0b013e318158343b
  • Journal Name: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.61-62
  • Keywords: vincristine, rhabdomyosarcoma, neurogenic bladder, peripheral neuropathy, children, NEUROTOXICITY, AGENTS, ATONY
  • Gazi University Affiliated: Yes

Abstract

Vincristine commonly induces peripheral neuropathy but rarely causes voiding dysfunction. In this report, we describe a case of neurogenic bladder and peripheral neuropathy caused by the neurotoxic effect of vincristine and documented by urodynamic testing and electromyography. Neurologic evaluation aided in monitoring and understanding this problem.