GCF MMP-8 levels in smokers and non-smokers with chronic periodontitis following scaling and root planing accompanied by systemic use of flurbiprofen

Kurtis B., Tueter G., SERDAR M. A., Pinar S., Demirel I., Toyman U.

JOURNAL OF PERIODONTOLOGY, vol.78, no.10, pp.1954-1961, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 78 Issue: 10
  • Publication Date: 2007
  • Doi Number: 10.1902/jop.2007.070149
  • Journal Name: JOURNAL OF PERIODONTOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1954-1961
  • Keywords: chronic periodontitis, flurbiprofen/therapeutic use, gingival crevicular fluid, matrix metalloproteinase-8, smoking, GINGIVAL CREVICULAR FLUID, MATRIX-METALLOPROTEINASE INHIBITOR, SUBANTIMICROBIAL DOSE DOXYCYCLINE, LOCALLY DELIVERED DOXYCYCLINE, PROSTAGLANDIN E-2, ADULT PERIODONTITIS, SMOKING-CESSATION, CIGARETTE-SMOKING, ADJUNCTIVE USE, THERAPY
  • Gazi University Affiliated: Yes

Abstract

Background: Cigarette smoking has been identified as an important risk factor for the initiation and progression of chronic periodontitis (CP). The aim of this study was to investigate the effects of phase I periodontal therapy and adjunctive flurbiprofen administration on matrix metalloproteinase (MMP)-8 levels in gingival crevicular fluid (GCF) samples from smoking and non-smoking patients with CP.