Genetic polymorphisms of FSHR, CYP17, CYP1A1, CAPN10, INSR, SERPINE1 genes in adolescent girls with polycystic ovary syndrome

CİNAZ P., Yesilkaya E., Tugba T. U., KONAÇ E., Yilmaz A., BİDECİ A., ...Daha Fazla

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS, cilt.26, sa.4, ss.205-216, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 4
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1007/s10815-009-9308-8
  • Dergi Adı: JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.205-216
  • Anahtar Kelimeler: Adolescent girl, Genetic polymorphisms, Polycystic ovary syndrome, FOLLICLE-STIMULATING-HORMONE, INSULIN-RECEPTOR GENE, SINGLE NUCLEOTIDE POLYMORPHISM, TYPE-2 DIABETES-MELLITUS, CALPAIN-10 GENE, CANCER SUSCEPTIBILITY, GENOMIC VARIANTS, CHILEAN WOMEN, CHINESE WOMEN, PAI-1 GENE
  • Gazi Üniversitesi Adresli: Evet

Özet

Polycystic ovary syndrome (PCOS), whose genetic basis is not completely well understood, is the most common endocrine disorder in women and it typically develops during adolescence. The aim of this study is to investigate the possible association between single nucleotide polymorphisms (SNPs) of FSHR, CYP17, CYP1A1, CAPN10, INSR, SERPINE1 genes and PCOS in adolescent girls.