Mu-opioid receptor binding measured by [C-11]carfentanil positron emission tomography is related to craving and mood in alcohol dependence

Bencherif B., Wand G., McCaul M., Kim Y., Iigin N., Dannals R., ...Daha Fazla

BIOLOGICAL PSYCHIATRY, cilt.55, sa.3, ss.255-262, 2004 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 55 Sayı: 3
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1016/j.biopsych.2003.07.007
  • Dergi Adı: BIOLOGICAL PSYCHIATRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.255-262
  • Anahtar Kelimeler: Mu opioid receptors, alcoholism, craving, depression, PET imaging, COMPULSIVE DRINKING SCALE, BRAIN METABOLIC-CHANGES, FAMILY-HISTORY, ETHANOL-CONSUMPTION, BETA-ENDORPHIN, PSYCHOMETRIC PROPERTIES, NALTREXONE, RATS, NALOXONE, PREFERENCE
  • Gazi Üniversitesi Adresli: Evet

Özet

Background: The endogenous opioid system has been linked to alcohol dependence through animal and human studies. We investigated the relationship between alcohol craving and brain mu opioid receptors (R-OR) in alcohol-dependent subjects.