Successful treatment of refractory listeria meningitis and bacteremia with trimethoprim-sulfamethoxazole in an immunocompetent child

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Polat M., Kara S. S., TAPISIZ A., DERİNÖZ GÜLERYÜZ O., ÇAĞLAR K., TEZER H.

TURKISH JOURNAL OF PEDIATRICS, vol.58, no.2, pp.220-222, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 58 Issue: 2
  • Publication Date: 2016
  • Doi Number: 10.24953/turkjped.2016.02.017
  • Journal Name: TURKISH JOURNAL OF PEDIATRICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.220-222
  • Keywords: immunocompetent child, Listeria meningitis, trimethoprim-sulfamethoxazole
  • Gazi University Affiliated: Yes

Abstract

Listeria monocytogenes is an important cause of life-threatening bacteremia and meningoencephalitis in neonates, pregnant women, the elderly, and immunocompromised individuals. However, it is an uncommon cause of illness in immunocompetent children beyond the neonatal period. Ampicillin with or without an aminoglycoside remains the best treatment for listeriosis. Here, we report a rare case of Listeria meningitis and bacteremia in a 7-month-old immunocompetent girl, which was refractory to ampicillin plus gentamicin treatment and successfully treated by the addition of TMP/SMX.