The effect of surgical and chemical denervation on ischaemia/reperfusion injury of skeletal muscle


Kucuker I., TUNCER S., Sencan A., Bircan F., Caglar E., ELMAS Ç., ...Daha Fazla

JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY, cilt.65, sa.2, ss.240-248, 2012 (SCI-Expanded) identifier identifier identifier

Özet

Introduction: Denervation decreases skeletal muscle's energy needs and alters its metabolism and circulation. Our study was designed in two stages to investigate the effects of surgical and chemical denervation on the ischaemia/reperfusion injury of skeletal muscle. Degenerative histological analysis, apoptosis scoring and tissue levels of malonyl-di-aldehyde (MDA) and nitric oxide end products (NOx) were studied to understand the extent of ischaemia/reperfusion injury of skeletal muscles.