Serum leptin levels are associated with tamoxifen-induced hepatic steatosis.


Gunel N., Coskun U., Toruner F. S., Sancak B., Yilmaz E., Cengiz O., ...More

Current medical research and opinion, vol.19, no.1, pp.47-50, 2003 (SCI-Expanded, Scopus) identifier identifier identifier

Abstract

Purpose: Tamoxifen, used in breast cancer treatment, may induce hepatic steatosis. It has been suggested that leptin, which, has a relationship with body fat stores, may be involved in the pathogenesis of hepatic steatosis. In this study, we compared serum leptin levels in tamoxifen-treated patients with and without hepatic steatosis.