Association of matrix metalloproteinase-1, matrix metalloproteinase-9, tissue inhibitor of matrix metalloproteinase-1, and interleukin-6 with epicardial and myocardial perfusion

Tanindi A., ŞAHİNARSLAN A., Elbeg S., CEMRİ M.

CORONARY ARTERY DISEASE, vol.22, no.4, pp.253-258, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 22 Issue: 4
  • Publication Date: 2011
  • Doi Number: 10.1097/mca.0b013e328343fc18
  • Journal Name: CORONARY ARTERY DISEASE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.253-258
  • Keywords: interleukin-6, matrix metalloproteinase, myocardial blush grade, Thrombolysis in Myocardial Infarction frame count, ACUTE CORONARY SYNDROME, CHRONIC KIDNEY-DISEASE, ANEURYSM FORMATION, INFARCTION, REPERFUSION, TIMP-1, PLAQUE, ARTERY, AND-3, MICE
  • Gazi University Affiliated: Yes

Abstract

Objectives Matrix metalloproteinases (MMPs), which are important regulators of extracellular matrix degradation, are known to induce atherosclerotic plaque rupture because of the degradation of collagen fibers in the fibrous cap. We aimed to investigate the possible association between these enzymes and objective coronary angiographic parameters of epicardial or myocardial perfusion.