Diagnostic value of neopterin during neutropenic fever and determination of disease activity in childhood leukemias

Belen F. B., KOÇAK Ü., Albayrak M., KAYA Z., Gursel T.

DISEASE MARKERS, vol.33, no.1, pp.11-18, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 33 Issue: 1
  • Publication Date: 2012
  • Doi Number: 10.1155/2012/474085
  • Journal Name: DISEASE MARKERS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.11-18
  • Gazi University Affiliated: Yes


Neopterin, a pteridine group compound that is secreted from macrophages is shown to be increased in adult leukemia; however there are few studies in childhood leukemia. This study aimed to investigate neopterin levels during childhood leukemia treatment and neutropenic fever episodes for the possibility of using as a marker for disease activity and differentiation of infections.