Useful agents against aflatoxin B-1 - antibacterial azomethine and Mn(III) complexes involving L-Threonine, L-Serine, and L-Tyrosine
ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY, cilt.44, ss.853-858, 2016 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 44
- Basım Tarihi: 2016
- Doi Numarası: 10.3109/21691401.2014.991792
- Dergi Adı: ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.853-858
- Anahtar Kelimeler: antimicrobial properties, aflatoxin B, Mn(III) complexes, mutagenicity, AMINO-ACIDS, EPOXIDATION, GLUTAMINE
- Gazi Üniversitesi Adresli: Evet
Özet
The present study is focused on evaluating the antimutagenic properties of Schiff bases and Mn(III) complexes with L-Threonine, L-Serine and L-Tyrosine, which have antimicrobial activity. These six compounds were investigated for antimutagenic properties against Afl atoxin B ı (AFB ı ) by the micronucleus (MN) assay in a human lymphocyte cell culture in vitro. The protective role of these compounds against AFB ı -induced MN is probably related to its doses. A mechanism has been proposed to reduce the effect of AFB ı .