Atrial natriuretic peptide levels in rheumatic mitral regurgitation and response to angiotensin-converting enzyme inhibitors

Kula S., Tunaoglu F., Olgunturk R., Gokcora N.

CANADIAN JOURNAL OF CARDIOLOGY, vol.19, no.4, pp.405-408, 2003 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 4
  • Publication Date: 2003
  • Journal Name: CANADIAN JOURNAL OF CARDIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.405-408
  • Keywords: angiotensin-converting enzyme inhibitors, atrial natriuretic peptide, rheumatic mitral regurgitation, CONGESTIVE-HEART-FAILURE, PLASMA
  • Gazi University Affiliated: Yes

Abstract

BACKGROUND: Rheumatic mitral regurgitation (MR) causes heart failure by volume overload and an increase in atrial natriuretic peptide (ANP) levels by atrial stretching. Symptoms of heart failure improve with ANP treatment. Angiotensin-converting enzyme inhibitors (ACEI) and ANP have similar effects, such as vasodilation, natriuresis and diuresis.