Serum Sphingosine 1 Phosphate Levels in Patients with and without Coronary Collateral Circulation

Kiziltunc E., Gok M., Topcuoglu C., Kundi H., Cetin M., Turhan T., ...More

ACTA CARDIOLOGICA SINICA, vol.34, no.5, pp.379-385, 2018 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 5
  • Publication Date: 2018
  • Doi Number: 10.6515/acs.201809_34(5).20180405a
  • Journal Name: ACTA CARDIOLOGICA SINICA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.379-385
  • Keywords: Coronary artery disease, Coronary collateral, Sphingosine 1 phosphate, CHRONIC TOTAL OCCLUSION, RETROGRADE APPROACH, GROWTH-FACTOR, 1-PHOSPHATE, SPHINGOSINE-1-PHOSPHATE, FLOW, ANGIOPLASTY, INFARCTION, OUTCOMES, RELEASE
  • Gazi University Affiliated: No

Abstract

Background: Sphingosine 1 phosphate, an active sphingolipid metabolite, functions in both healthy and diseased cardiovascular systems. It has been reported to play a role in angiogenesis and arteriogenesis in various tissues, which are the proposed mechanisms for the development of coronary collateral circulation. To the best of our knowledge, no data exist regarding serum sphingosine 1 phosphate levels and the presence of coronary collateral circulation in the literature. Thus this study aimed to investigate serum sphingosine 1 phosphate levels in patients with and without coronary collateral circulation.