Akademik Veri Yönetim Sistemi
Turk Anesteziyoloji ve Reanimasyon, cilt.29, sa.2, ss.73-78, 2001 (Scopus)
In this study, we have compared the neuromuscular blockage times, quality of muscle relaxation for endotracheal entubation and haemodynamic effects of non depolarizing muscle relaxants atracurium, vecuronium, rocuronium, under isoflurane inhalation anaesthesia. We included in our study 45 female ASA I-II class patients. To all patients; 7 mg/kg thiopentone for induction and isoflurane 1.5% in N2O 50%, O2 50% for maintainence were used. Patients were divided into 3 equal groups according to the neuromuscular blocking agent used: Group I 0.6 mg/kg atracurium, Group II 0.1 mg/kg vecuronium, Group III 0.6 mg/kg rocuronium. After 12 seconds via TOF-Guard monitorization when single twitch decreased to 10%, endotracheal entubation was performed. Quality of endotracheal entubation was acceptable (excellent and good) for all three groups. Onset of neuromuscular blockage was significantly shorter in rocuronium group comparing other two groups. As a result, we concluded that rocuronium as a nondepolarizing muscle relaxant with significantly shorter onset action and less cardiovascular and autonomic side effects may be an alternative to the depolarizing muscle relaxants.