The effects of low and high doses of sugammadex on kidney tissue in streptozotocin-induced diabetic rats

Kip, G.; Turgut, H.; Alkan, METİN; AYDIN, Muhammed; Erbatur, M.; Kiraz, H.; Kartal, S.; Boyunaga, H.; Comu, F.; ERDEM, OSMAN; Arslan, MUSTAFA; Unal, Y.

doi:10.4149/bll_2015_146

The effects of low and high doses of sugammadex on kidney tissue in streptozotocin-induced diabetic rats

Kip G., Turgut H. C., Alkan M., AYDIN M. E., Erbatur M. E., Kiraz H. A., ...More

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, vol.116, no.12, pp.746-750, 2015 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 116 Issue: 12
Publication Date: 2015
Doi Number: 10.4149/bll_2015_146
Journal Name: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.746-750
Keywords: sugammadex, streptozotocin, diabetes, renal damage, CAPILLARY ENDOTHELIAL FENESTRATION, INDUCED NEUROMUSCULAR BLOCKADE, STAGE RENAL-FAILURE, PODOCYTE DETACHMENT, ROCURONIUM, REVERSAL, SAFETY, MULTICENTER, EFFICACY
Open Archive Collection: AVESIS Open Access Collection
Gazi University Affiliated: Yes

Abstract

BACKGROUND: Sugammadex is primarily excreted via renal route. We investigated effects of low and high doses of sugammadex (16 mg/kg versus 96 mg/kg) on renal tissue samples of streptozotocin-induced diabetic rats.