The effects of low and high doses of sugammadex on kidney tissue in streptozotocin-induced diabetic rats

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Kip G., Turgut H. C., Alkan M., AYDIN M. E., Erbatur M. E., Kiraz H. A., ...More

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, vol.116, no.12, pp.746-750, 2015 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 116 Issue: 12
  • Publication Date: 2015
  • Doi Number: 10.4149/bll_2015_146
  • Journal Name: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.746-750
  • Keywords: sugammadex, streptozotocin, diabetes, renal damage, CAPILLARY ENDOTHELIAL FENESTRATION, INDUCED NEUROMUSCULAR BLOCKADE, STAGE RENAL-FAILURE, PODOCYTE DETACHMENT, ROCURONIUM, REVERSAL, SAFETY, MULTICENTER, EFFICACY
  • Open Archive Collection: AVESIS Open Access Collection
  • Gazi University Affiliated: Yes

Abstract

BACKGROUND: Sugammadex is primarily excreted via renal route. We investigated effects of low and high doses of sugammadex (16 mg/kg versus 96 mg/kg) on renal tissue samples of streptozotocin-induced diabetic rats.