Voltammetric Determination of Ophthalmic Drug Dexamethasone Using Poly-glycine Multi Walled Carbon Nanotubes Modified Paste Electrode

Demir E., İnam O., İnam R., Aboul-Enein H. Y.

CURRENT ANALYTICAL CHEMISTRY, cilt.14, sa.1, ss.83-89, 2018 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 1
  • Basım Tarihi: 2018
  • Doi Numarası: 10.2174/1573411013666161219161320
  • Dergi Adı: CURRENT ANALYTICAL CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.83-89
  • Anahtar Kelimeler: Dexamethasone, ophthalmic drug, modified electrode, voltammetry, determination, carbon nanotubes, DIFFERENTIAL-PULSE POLAROGRAPHY, LIQUID-CHROMATOGRAPHY, PHARMACEUTICAL FORMULATIONS, BIOLOGICAL-FLUIDS, DOSAGE FORM, HPLC METHOD, PLASMA, BETAMETHASONE, VALIDATION, SAMPLES
  • Gazi Üniversitesi Adresli: Evet

Özet

Background: Dexamethasone has been used in ophthalmology for the treatment of different eye diseases and it is a powerful synthetic member of the glucocorticoid class of steroid medicament having anti-inflammatory and immunosuppressant characteristics. The aim of this study is to develop a rapid, sensitive and selective voltammetric method for its determination using polygylcine-multi walled carbon nanotubes (polyglycine-MWCNTs) modified paste electrode.