Evaluation of Risk Factors, Clinical Characteristics, and Prognosis in Cerebral Venous Thrombosis: A Single Tertiary Center Experience

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Mutlucan H. M., Batur Çağlayan H. Z., Nazlıel B., Tokgöz N., Uçar M.

MEANDROS MEDICAL AND DENTAL JOURNAL, cilt.23, sa.3, ss.355-360, 2022 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 23 Sayı: 3
  • Basım Tarihi: 2022
  • Doi Numarası: 10.4274/meandros.galenos.2022.26986
  • Dergi Adı: MEANDROS MEDICAL AND DENTAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI)
  • Sayfa Sayıları: ss.355-360
  • Anahtar Kelimeler: Cranial cerebral venous sinus thrombosis, erythrocyte indices sinus sagittalis superior, transverse sinus thrombosis venous infarct
  • Gazi Üniversitesi Adresli: Evet

Özet

Objective:

We evaluated the demographic and clinical characteristics, risk factors, involved vasculature, and prognosis in cerebral venous thrombosis.

Materials and Methods:

We included 53 patients with cerebral venous thrombosis (CVT) who were followed up in our neurology inpatient clinic and neurology intensive care unit in the study. The demographic and clinical characteristics on admission, risk factors, results of laboratory tests and neuroimaging studies, treatment, outcomes at discharge, and 6th-month follow-up were reviewed.

Results:

The mean age of the patients was 44.1±13.7 (19-71) years. Thirty-one (58.4%) of the patients were female. The most frequent symptom was headache (69.8%). Puerperium and malignancy were the most common risk factors for patients under 45 years of age; whereas anemia and malignancy were the most common risk factors for patients over 45 years of age. The most common localization of CVT was found to be the transverse sinus (69.8%). The modified Rankin scale (mRS) scores at discharge were 0 for 47 patients (88.6%), 1 for 4 patients (7.5%) and 4 for 2 patients. In the 6th-month follow-up, 48 (90.5 %) of the patients had an mRS score of 0 with normal neurological examination.

Conclusion:

Our study, representing the experience of a single tertiary referral center, showed that CVT mostly affected women of reproductive ages. More than 90% of patients in our study had an mRS score of 0 at the 6th-month followup. The results of our study suggest that early diagnosis of CVT with advanced neuroimaging techniques recently has improved the outcomes and reduced the disability.