Lack of nitrate tolerance in isosorbid dinitrate- and sodium nitroprusside-induced relaxation of rabbit internal anal sphincter

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KOYUNCU A., BAĞÇİVAN İ., SARAÇ B., Aydin C., YILDIRIM Ş., Sarioglu Y.

WORLD JOURNAL OF GASTROENTEROLOGY, vol.14, no.29, pp.4667-4671, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 14 Issue: 29
  • Publication Date: 2008
  • Doi Number: 10.3748/wjg.14.4667
  • Journal Name: WORLD JOURNAL OF GASTROENTEROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.4667-4671
  • Gazi University Affiliated: Yes

Abstract

AIM: To investigate the tolerance development against the relaxant effect of nitric oxide donating drug isosorbide dinitrate (ISDN) and sodium nitropruside (SNP) in internal anal sphincter (IAS) smooth muscle.