Lack of nitrate tolerance in isosorbid dinitrate- and sodium nitroprusside-induced relaxation of rabbit internal anal sphincter

KOYUNCU, AYHAN; BAĞÇİVAN, İHSAN; SARAÇ, BÜLENT; Aydin, Cengiz; YILDIRIM, ŞAHİN; Sarioglu, Yusuf

doi:10.3748/wjg.14.4667

Lack of nitrate tolerance in isosorbid dinitrate- and sodium nitroprusside-induced relaxation of rabbit internal anal sphincter

KOYUNCU A., BAĞÇİVAN İ., SARAÇ B., Aydin C., YILDIRIM Ş., Sarioglu Y.

WORLD JOURNAL OF GASTROENTEROLOGY, vol.14, no.29, pp.4667-4671, 2008 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 14 Issue: 29
Publication Date: 2008
Doi Number: 10.3748/wjg.14.4667
Journal Name: WORLD JOURNAL OF GASTROENTEROLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.4667-4671
Open Archive Collection: AVESIS Open Access Collection
Gazi University Affiliated: Yes

Abstract

AIM: To investigate the tolerance development against the relaxant effect of nitric oxide donating drug isosorbide dinitrate (ISDN) and sodium nitropruside (SNP) in internal anal sphincter (IAS) smooth muscle.