Lead compounds and drug candidates from some Turkish plants for human health


ERDOĞAN ORHAN İ., Sener B.

LEAD MOLECULES FROM NATURAL PRODUCTS: DISCOVERY AND NEW TRENDS, cilt.2, ss.331-352, 2006 (SCI-Expanded) identifier identifier

Özet

Biodiversity has tremendous potential in having excellent chemical diversity to drug discovery programs and in serving as templates for synthetic drugs. Research activities on plants growing in Turkey, showed that diverse classes of bioactive compounds ranging from simple aromatics, e. g. paeonol, to complex molecules of alkaloids, terpenoids and steroids possess significant biological activities, including anticholinesterase, anticholinergic, antihypertensive, antithrombocyter, anti-inflammatory, antimalarial and antibacterial. The results of these investigations and their potential therapeutic application have been reviewed in this chapter.