BONE REACTION TO SUBPERIOSTEALLY IMPLANTED HYDROXYAPATITE COLLAGEN GLYCOSAMINOGLYCANS AND CORAL IN THE GUINEA-PIG


ALPASLAN C., ALPASLAN G., OYGUR T.

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS, vol.77, no.4, pp.335-340, 1994 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 77 Issue: 4
  • Publication Date: 1994
  • Doi Number: 10.1016/0030-4220(94)90193-7
  • Journal Name: ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS
  • Journal Indexes: Science Citation Index Expanded, Scopus, BIOSIS, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.335-340

Abstract

Tissue reactions and new bone formation at 30, 60, and 90 days after the subperiosteal implantation of hydroxyapatite/collagen/glycosaminoglycans and blocks of coral in 18 guinea pigs were evaluated histologically with the use of polarized light and light microscopy. Animals implanted with coral showed new bone formation at each time interval and resorption of coral was observed. Histopathologic evaluation of hydroxyapatite/collagen/glycosaminoglycans implants revealed no evidence of new bone formation and the hydroxyapatite particles were surrounded by fibrous connective tissue.