The Relationship Between Epicardial Adipose Tissue Thickness and Infarct-Related Artery Patency in Patients With ST-Segment Elevation Myocardial Infarction

Sen F., Yilmaz S., Balci K. G., Gul M., Balci M. M., Akboga M. K., ...Daha Fazla

ANGIOLOGY, cilt.67, sa.3, ss.281-286, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 67 Sayı: 3
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1177/0003319715591330
  • Dergi Adı: ANGIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.281-286
  • Anahtar Kelimeler: epicardial adipose tissue thickness, infarct-related artery, acute coronary syndrome, PRIMARY ANGIOPLASTY, CORONARY FLOW, DISEASE, FAT, INTERVENTION, REPERFUSION, MORTALITY, OUTCOMES, ECHOCARDIOGRAPHY, ATHEROSCLEROSIS
  • Gazi Üniversitesi Adresli: Hayır

Özet

We investigated the relationship between epicardial adipose tissue (EAT) and infarct-related artery (IRA) patency before mechanical reperfusion in patients with ST-segment elevation myocardial infarction (STEMI). Patients (n = 640) were divided into 2 groups based on the thrombolysis in myocardial infarction (TIMI) flow grade. Impaired flow was defined as TIMI grades 0, 1, and 2, and normal flow was defined as TIMI 3. On the admission angiography, 65 (10.2%) patients had TIMI 3 flow, and the remaining 575 (89.8%) had TIMI 0, 1, or 2 flow. The impaired flow group patients had a higher incidence of diabetes mellitus (53.7% vs 41.5%, P = .035), higher EAT thickness (5.66 +/- 1.84 vs 4.87 +/- 2.09 mm, P = .001), and lower ejection fraction (43.1% +/- 8.9% vs 47.4% +/- 9.1%, P = .025). Multivariate stepwise logistic regression analysis showed that IRA patency was independently associated with EAT thickness (odds ratio [OR] 0.785; 95% confidence interval [CI] 0.712-0.858; P = .001) and neutrophil-lymphocyte ratio (OR 0.815; 95% CI 0.732-0.917; P = .025). Thickness of EAT was an independent predictor of lower TIMI flow in IRA in patients with STEMI.