Assessment of Vascular Endothelial Growth Factor and Matrix Metalloproteinase-9 in the Periodontium of Rats Treated With Atorvastatin

Balli U., KELEŞ G., ÖZKAN ÇETİNKAYA B., Mercan U., AYAS B., Erdogan D.

JOURNAL OF PERIODONTOLOGY, cilt.85, sa.1, ss.178-187, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 85 Sayı: 1
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1902/jop.2013.130018
  • Dergi Adı: JOURNAL OF PERIODONTOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.178-187
  • Anahtar Kelimeler: Atorvastatin, histology, immunohistochemistry, periodontal disease, rats, GINGIVAL CREVICULAR FLUID, ALVEOLAR BONE LOSS, HMG-COA REDUCTASE, MATRIX METALLOPROTEINASES, TISSUE INHIBITORS, SIMVASTATIN, EXPRESSION, MMP-9, DEFECTS, ANGIOGENESIS
  • Gazi Üniversitesi Adresli: Evet

Özet

Background: The aim of this study is to examine, for the first time, the role of systemic and local atorvastatin application on periodontium using histomorphometric and immunohistochemical analysis during and after experimental periodontitis induction with or without the presence of microbial dental biofilm.