Atherogenic lipoprotein phenotype and LDL size and subclasses in women with gestational diabetes

Rizzo M., Berneis K., Altinova A., Toruner F. S., Akturk M. Y., Ayvaz G., ...More

DIABETIC MEDICINE, vol.25, no.12, pp.1406-1411, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 12
  • Publication Date: 2008
  • Doi Number: 10.1111/j.1464-5491.2008.02613.x
  • Journal Name: DIABETIC MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1406-1411
  • Keywords: dense LDL, diabetes, HDL-cholesterol, pregnancy, small, triglycerides, LOW-DENSITY LIPOPROTEINS, ENZYMATIC DETERMINATION, MELLITUS, LIPIDS, RISK, SUBFRACTIONS, METABOLISM, PREGNANCY
  • Gazi University Affiliated: Yes

Abstract

Women with gestational diabetes are more likely to develop Type 2 diabetes and cardiovascular disease after pregnancy; however, the exact nature of the lipid alterations present is not clear. In Mediterranean women with gestational diabetes, we measured low-density lipoprotein (LDL) size and all seven subclasses, as well as the 'atherogenic-lipoprotein phenotype' [ALP, e.g. concomitant presence of elevated triglycerides, reduced high-density lipoprotein (HDL)-cholesterol and increased small, dense LDL].