Challenge-proven nonsteroidal anti-inflammatory drug hypersensitivity in children

Yilmaz O., Karagol I. H. E., Bakirtas A., Topal E., Celik G. E., Demirsoy M. S., ...Daha Fazla

ALLERGY, cilt.68, sa.12, ss.1555-1561, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 68 Sayı: 12
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1111/all.12266
  • Dergi Adı: ALLERGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1555-1561
  • Anahtar Kelimeler: drug allergy, pediatrics, PROVOCATION TESTS, NSAID HYPERSENSITIVITY, COX-2 INHIBITORS, PARACETAMOL, DIAGNOSIS, MELOXICAM, SAFETY, IGE
  • Gazi Üniversitesi Adresli: Evet

Özet

BackgroundFew studies investigated hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs) in children. The objective was to determine the frequency of true NSAID hypersensitivity (NSAID-H) and whether there were any parameters in the history of children that would predict NSAID-H. Secondly, an investigation was conducted into whether NSAID-hypersensitive children could tolerate safe alternatives. Differing from previous studies, the researchers followed the recent diagnostic algorithm proposed for acute reactions in NSAID-H.