Acute Megakaryoblastic Leukemia with t(1;22) Mimicking Neuroblastoma in an Infant

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Gokce M., AYTAÇ EYÜPOĞLU Ş. S., ÜNAL S., Altan İ., GÜMRÜK F., Cetin M.

TURKISH JOURNAL OF HEMATOLOGY, cilt.32, sa.1, ss.64-67, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Sayı: 1
  • Basım Tarihi: 2015
  • Doi Numarası: 10.4274/tjh.2013.0189
  • Dergi Adı: TURKISH JOURNAL OF HEMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.64-67
  • Gazi Üniversitesi Adresli: Hayır

Özet

Acute megakaryoblastic leukemia (AMKL) with t(1;22) (p13;q13) is an extremely rare subtype of acute myeloid leukemia that is almost always described in infants. t(1;22) (p13;q13)-positive AMKL with extramedullary infiltration has been previously reported only once in the literature. Herein, we report a 3-month-old infant presenting with a pelvic mass and pancytopenia suggesting neuroblastoma. Bone marrow evaluation revealed t(1;22)-positive AMKL that responded well to a regimen containing high-dose cytarabine.