CURRENT MEDICAL RESEARCH AND OPINION, vol.19, no.3, pp.226-237, 2003 (SCI-Expanded)
Article / Article
CURRENT MEDICAL RESEARCH AND OPINION
Science Citation Index Expanded (SCI-EXPANDED), Scopus
amlodipine, antihypertensive agents, calcium channel blockers, clinical trials, GITS, hypertension, essential, nifedipine, CORONARY-ARTERY DISEASE, QUALITY-OF-LIFE, ANTAGONISTS, DILTIAZEM, PHARMACOKINETICS, TOLERABILITY, PERSISTENCE, EFFICACY, TRIAL
Gazi University Affiliated:
Background: Hypertension is one of the most important causes of cardiovascular disease, and treatment of hypertension leads to a significant reduction in cardiovascular mortality and morbidity. Although calcium channel blockers are regarded as an important part of the therapeutic armamentarium against cardiovascular diseases, and are among the most frequently prescribed anti hypertensive medications, concern has been aroused about these drugs, particularly the short-acting dihydropyridine derivatives. However, the value of nifedipine GITS (Adalat-Crono*), the long-acting dihydropyridine, is in need of being re-established.