A Rare Neoplasm of the Kidney: A Female Patient as the First Case Possibly Triggered by Pregnancy

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Erten K. Ş., Çetin S., Urgancı M., Gönül İ. I., Tan M. Ö.

Journal of Urological Surgery, vol.12, no.2, pp.112-114, 2025 (ESCI, Scopus, TRDizin) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 12 Issue: 2
  • Publication Date: 2025
  • Doi Number: 10.4274/jus.galenos.2024.2024-3-10
  • Journal Name: Journal of Urological Surgery
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.112-114
  • Keywords: early age, Mixed epithelial stromal tumor, pregnancy
  • Gazi University Affiliated: Yes

Abstract

Mixed epithelial and stromal tumor (MEST) is a rare, biphasic adult renal tumor composed of solid and cystic areas with spindle cell stroma and epithelium. Tumors expressing estrogen and progesterone receptors are affected by hormonal changes, often in post-menopausal women on hormone replacement therapy. Since it can be challenging to differentiate between MEST and malignant tumors, it should be considered as a differential diagnosis. To our knowledge, this is the first case postulated to be caused possibly by pregnancy-related hormonal changes. It is noteworthy that the tumor is affected by changing estrogen and progesterone hormone levels during pregnancy, thus rapidly progressing in a brief time.