Journal of Urological Surgery, cilt.12, sa.2, ss.112-114, 2025 (ESCI, Scopus, TRDizin)
Mixed epithelial and stromal tumor (MEST) is a rare, biphasic adult renal tumor composed of solid and cystic areas with spindle cell stroma and epithelium. Tumors expressing estrogen and progesterone receptors are affected by hormonal changes, often in post-menopausal women on hormone replacement therapy. Since it can be challenging to differentiate between MEST and malignant tumors, it should be considered as a differential diagnosis. To our knowledge, this is the first case postulated to be caused possibly by pregnancy-related hormonal changes. It is noteworthy that the tumor is affected by changing estrogen and progesterone hormone levels during pregnancy, thus rapidly progressing in a brief time.