EXPERIMENTAL AND CLINICAL TRANSPLANTATION, cilt.23, sa.7, ss.460-465, 2025 (SCI-Expanded)
Objectives: Renal transplant is the most appropriate treatment for adult and pediatric patients with end-stage renal failure. Materials and Methods: Fifty-one pediatric kidney transplants were performed in 49 pediatric recipients from a total of 263 kidney recipients at the Gazi University Transplantation Center (T & uuml;rkiye) between January 2006 and January 2021. We gathered and analyzed data retrospectively from hospital medical records of pediatric transplant recipients. Results: Kidney grafts were obtained from 18 deceased (35%) and 33 living donors (65%). Among 51 pediatric renal transplants, 10 (19.6%) had complications, with 6 early and 4 late complications. Among 6 early complications posttransplant, 5 were surgical complications (9.8%) and 1 (1.9%) was urologic (1.9%), but no vascular complications were seen. Among 5 surgical complications, 3 (5.8%) were lymphocele and 2 were (3.9%) bleeding complications. Among 4 patients with late complications, 2 had renal artery stenosis and 2 had ureter stenosis. Two patients required re-transplantation because of graft loss from BK virus nephropathy and chronic allograft nephropathy. Among 51 pediatric kidney transplants, 15 recipients (29.4%) presented with 27 cases of infection. Twentyone acute rejection episodes were seen in 14 of 51 pediatric transplant procedures (27.4%), and 4 humoral rejections occurred in 3 of 51 pediatric transplant procedures (5.8%). In addition, 27 renal transplant patients (52.9%) had normal graft functions at median follow-up of 95 months (98.7 +/- 57.7; range, 58-233 mo). Twenty-eight of 51 patients (54.9%) lost kidney grafts over a 15-year follow-up. No graft loss or patient deaths occurred because of surgical complications. Conclusions: In analysis of 15 years of experience in pediatric renal transplants, our results were within results of other series. Pediatric renal transplant is a safe procedure in our department, based on patient and graft survivals, with no graft loss from surgical complications.