Ganglioglioma with lytic skull lesions: a case report

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Gurkanlar D., Kocak H., Yucel E., Aciduman A., Gunaydin A., Ekinci O., ...More

NEUROCIRUGIA, vol.18, no.2, pp.123-126, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 18 Issue: 2
  • Publication Date: 2007
  • Doi Number: 10.1016/s1130-1473(07)70297-x
  • Journal Name: NEUROCIRUGIA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.123-126
  • Gazi University Affiliated: No


Gangliogliomas represent only 0.4% of central nervous system neoplasms and 1.3% of brain tumors. They are benign neoplasms with low morbidity and mortality and the patients usually present with seizures, but there has been no adult ganglioglioma with lytic skull lesion. A 49-year-old right handed woman suffering from generalized epileptic seizures was admitted to our hospital. She had also left hemiparesis with 4/5 motor strength. Magnetic resonance imaging and immunohistochemical studies revealed WHO Grade 11 ganglioglioma. Skull X-ray showed the lytic skull lesions. We have to consider gangliogliomas in the differential diagnosis of lytic skull lesions.