In vivo confocal microscopy and anterior segment optical coherence tomography follow-up of cysteamine treatment in corneal cystinosis

Ozdemir H. B., ÖZMEN M. C., AKTAŞ Z., Hasanreisoglu M.

INDIAN JOURNAL OF OPHTHALMOLOGY, vol.67, no.1, pp.153-155, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 67 Issue: 1
  • Publication Date: 2019
  • Doi Number: 10.4103/ijo.ijo_736_18
  • Journal Name: INDIAN JOURNAL OF OPHTHALMOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.153-155
  • Keywords: Anterior segment optical coherence tomography, cysteamine, cystinosis, in vivo confocal microscopy, NEPHROPATHIC CYSTINOSIS
  • Gazi University Affiliated: Yes

Abstract

A 36-year-old female presented initially with photophobia and visual deterioration. After examination and laboratory tests, patient was diagnosed with cystinosis. Cysteamine drops 4 x 1 drops/day was given as treatment for 1 year. During follow-up, in vivo confocal microscopy (IVCM) and anterior segment optical coherence tomography (AS-OCT) was performed. Photophobia was relieved and IVCM obtained the decrease in size and density of corneal crystals 1 year after. Depth of corneal crystals did not change but crystal density score reduced with cysteamine treatment.