Neutrophil-to-lymphocyte ratio and red cell distribution width: potential inflammatory markers for sudden sensorineural hearing loss


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KAYALI DİNÇ S., ÇAYÖNÜ M., BOYNUEĞRİ S., ŞAHİN M. M. , ERYILMAZ A.

JOURNAL OF CLINICAL AND ANALYTICAL MEDICINE, vol.10, no.2, 2019 (Journal Indexed in ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 10 Issue: 2
  • Publication Date: 2019
  • Doi Number: 10.4328/jcam.6077
  • Title of Journal : JOURNAL OF CLINICAL AND ANALYTICAL MEDICINE
  • Keywords: Sudden Sensorineural Hearing Loss, Neutrophil, Lymphocyte, Red Cell Distribution Width, Inflammation, PROGNOSIS, BIOMARKERS, INFARCTION, DIAGNOSIS, DEAFNESS

Abstract

Aim: In this study, we aimed to evaluate whether the neutrophil-to-lymphocyte (NLR) ratio and red cell distribution width (RDW) value, which are accepted as novel indicators of inflammation, can be indicators for the evaluation of inflammation in Sudden Sensorineural Hearing Loss (SSHL) disease or not. Material and Method: The patient group was diagnosed as SSHL in our clinic between January 2012 and September 2018. Control group was constituted from the participants who had normal audiometry findings. Hematologic parameters were recorded. NLR was calculated for the statistical analysis. Results: This study was carried out with 169 volunteers, between the age of 18 - 87 years. The mean age of the patients was 49.4 +/- 15 years. There was no difference between the groups in terms of age. RDW was found significantly higher in the study group than the control group. Also, we found that NLR was significantly higher in the patients with SSHL when compared to the control group. Discussion: The high level of NLR and RDW in this disease, which is thought to play a role in the etiology of many diseases, may be interpreted as a sign of inflammation on the basis of the disease. Considering the treatment for etiology, the importance of anti-inflammatory treatment is appreciated.