TUMORI J, vol.95, no.1, pp.87-90, 2009 (Journal Indexed in SCI)
Article / Article
Title of Journal :
cytarabine, mucosal damage, protection, mice, vitamin A, DEFICIENCY, TOXICITY, LEUKEMIA, ACIDS
Background. Cytarabine (ARA-C) has been used for many years in the treatment of patients with leukemia and lymphoma. Gastrointestinal ulceration and mucositis are two of the well-known side effects of ARA-C. We set out to investigate whether vitamin A (VA) can help prevent ARA-C-induced mucosal lesions in mice.