Polymorphisms related to estrogen and xenobiotic metabolism in healthy Turkish women


Kocabas N., Sardas S., Karakaya A.

ARCHIVES OF MEDICAL RESEARCH, vol.36, no.1, pp.19-23, 2005 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 36 Issue: 1
  • Publication Date: 2005
  • Doi Number: 10.1016/j.arcmed.2004.10.003
  • Title of Journal : ARCHIVES OF MEDICAL RESEARCH
  • Page Numbers: pp.19-23

Abstract

Background. Polymorphisms which are inherited alterations in the activity of cytochrome P450 1B1 (CYP1B1), catechol O-methyltransferase (COMT), manganese superoxide dismutase (MnSOD) hold the potential to define differences in estrogen metabolism and, thereby, possibly explain inter-individual differences in cancer susceptibility associated with estrogen-mediated carcinogenesis.