Improving the bioavailability and bioactivity of garlic bioactive compounds via nanotechnology

Lu X., Wang C., Zhao M., Wu J., Niu Z., Zhang X., ...Daha Fazla

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION, cilt.62, sa.30, ss.8467-8496, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 62 Sayı: 30
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1080/10408398.2021.1929058
  • Dergi Adı: CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, Aerospace Database, Agricultural & Environmental Science Database, Aquatic Science & Fisheries Abstracts (ASFA), Biotechnology Research Abstracts, CAB Abstracts, CINAHL, Communication Abstracts, Compendex, EMBASE, Food Science & Technology Abstracts, MEDLINE, Metadex, SportDiscus, Veterinary Science Database, Civil Engineering Abstracts
  • Sayfa Sayıları: ss.8467-8496
  • Anahtar Kelimeler: Nanotechnology, garlic bioactive compounds, bioavailability, bioactivity, applications, SOLID LIPID NANOPARTICLES, DIALLYL-DISULFIDE DADS, PROSTATE-CANCER CELLS, HUMAN GASTRIC-CANCER, TRISULFIDE INDUCES APOPTOSIS, NEGATIVE BREAST-CANCER, OIL-IN-WATER, STERICALLY STABILIZED LIPOSOMES, MEDIATED MULTIDRUG-RESISTANCE, ALLYLMERCAPTO-L-CYSTEINE
  • Gazi Üniversitesi Adresli: Evet

Özet

This review highlights main bioactive compounds and important biological functions especially anticancer effects of the garlic. In addition, we review current literature on the stability and bioavailability of garlic components. Finally, this review aims to provide a potential strategy for using nanotechnology to increase the stability and solubility of garlic components, providing guidelines for the qualities of garlic products to improve their absorption and prevent their early degradation, and extend their circulation time in the body. The application of nanotechnology to improve the bioavailability and targeting of garlic compounds are expected to provide a theoretical basis for the functional components of garlic to treat human health. We review the improvement of bioavailability and bioactivity of garlic bioactive compounds via nanotechnology, which could promisingly overcome the limitations of conventional garlic products, and would be used to prevent and treat cancer and other diseases in the near future.