PHYTOMEDICINE, vol.54, pp.259-264, 2019 (Journal Indexed in SCI)
Article / Article
Title of Journal :
Neurodegenerative disorders, Epilepsy, Zebrafish, Coumarins, Counter-current chromatography, Natural products, ANTICONVULSANT ACTIVITY, ZEBRAFISH, COUMARINS, CONSTITUENTS, FRUITS, CHOLINESTERASE, IMPERATORIN, INHIBITORS, DRUGS
Background: Medicinal plants are a proven source of drug-like small molecules with activity towards targets relevant for diseases of the central nervous system (CNS). Plant species of the Apiaceae family have to date yielded a number of neuroactive metabolites, such as coumarin derivatives with acetylcholinesterase inhibitory activity or anti-seizure activity.