PHYTOMEDICINE, vol.54, pp.259-264, 2019 (SCI-Expanded)
Article / Article
Science Citation Index Expanded (SCI-EXPANDED), Scopus
Neurodegenerative disorders, Epilepsy, Zebrafish, Coumarins, Counter-current chromatography, Natural products, ANTICONVULSANT ACTIVITY, ZEBRAFISH, COUMARINS, CONSTITUENTS, FRUITS, CHOLINESTERASE, IMPERATORIN, INHIBITORS, DRUGS
Gazi University Affiliated:
Background: Medicinal plants are a proven source of drug-like small molecules with activity towards targets relevant for diseases of the central nervous system (CNS). Plant species of the Apiaceae family have to date yielded a number of neuroactive metabolites, such as coumarin derivatives with acetylcholinesterase inhibitory activity or anti-seizure activity.