Corpus callosum morphology of healthy children: a structural magnetic resonance imaging study from Turkey
EUROPEAN JOURNAL OF ANATOMY, cilt.24, sa.6, ss.467-473, 2020 (ESCI, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 24 Sayı: 6
- Basım Tarihi: 2020
- Dergi Adı: EUROPEAN JOURNAL OF ANATOMY
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, EMBASE, DIALNET
- Sayfa Sayıları: ss.467-473
- Gazi Üniversitesi Adresli: Hayır
Özet
Morphological measurement of corpus callosum (CC) in magnetic resonance imaging studies has an important value for clinical decision-making during the period of childhood. Although there is evidence for differences in brain morphology in terms of socioeconomic disparities, there is no research specifically on CC morphology from any low- and middle-income countries. This study aims to report structural measurements and area of CC of healthy children from Turkey, a middle-income country, and find out whether the CC morphology differs between male and female children in different age groups. Healthy children aged 6-18 years were recruited retrospectively and their CC anteroposterior (AP) length, genu, body and splenium width (GW, BW, SW) and CC midsagittal area were measured from magnetic resonance imaging studies. Independent sample t-test was used to compare CC measurements of the sex and age groups. Pearson correlation test was used to determine linear correlations between age and CC parameters. The sample consisted of 200 healthy children; at least 5 female and 5 male children for each age; 103 (51.5%) females, 97 (45.5%) males. There was a positive correlation between the age and CC AP length (r=0.248, p<0.001) and SW (r=0.325, p<0.001) as well as midsagittal area (r=0.191, p<0.007). The CC AP length, GW, BW, SW and area were not different statistically between sex groups. This study is the first report providing age and sex-related morphological measurements of CC of healthy children in Turkey. The findings may be helpful for clinicians and researchers from Turkey as well as other low- and middle-income countries.