Factors affecting the coaggregation ability of vaginal Lactobacilli with Candida spp.

Ekmekci H., ASLIM B., ÖNAL DARILMAZ D.

ANNALS OF MICROBIOLOGY, vol.59, no.1, pp.163-167, 2009 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 59 Issue: 1
  • Publication Date: 2009
  • Doi Number: 10.1007/bf03175615
  • Journal Name: ANNALS OF MICROBIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.163-167
  • Keywords: coaggregation, Lactobacillus spp., Candida sp., vagina, probiotic, AGGREGATION-PROMOTING FACTOR, EPITHELIAL-CELLS, FUSOBACTERIUM, UROPATHOGENS, STRAINS, ADHERENCE, ALBICANS, WOMEN
  • Gazi University Affiliated: Yes

Abstract

In this study, the capacity of 30 strains of lactobacilli to coaggregate with Candida albicans ATCC 10239, C. albicans AJD 180 and Candida krusei ATCC 6258 were studied in vitro. A marked coaggregation with C. albicans was observed for two strains of Lactobacillus crispatus, a strain of Lactobacillus cellobiosus and a strain of Lactobacillus salivarius. Coaggregation occurred at a pH range from 3 to 7, some strains showing optimal binding at high and other strains at low pH. Treatment of lactobacilli at 70 or 85 degrees C for 20 min or treatment of the bacteria with pepsin abolished their capacity of coaggregation. The results may be of importance when trying to establish probiotics for vaginal use.