Aim: Recently, colonic manometry (CM) studies have been used increasingly in order to get more information about colonic motility. No CM study has not been reported from Turkey before, so, in this study we aimed to share the preliminary results of our department. Material and Method: An eight-channel catheter was inserted into the colon via colonoscope under general anesthesia. At least eight hours colonic activities were recorded continuously. During the study, mainly, fasting and post-prandial periods and post-enema response were recorded. Results: The first case was a 17 years old girl at and had severe constipation with megarectosigmoid. Although peristaltic activity was recorded proximal to the sigmoid, there was no peristaltism in dilated rectum and sigmoid, and later this part was removed. The second case was an 11 years old boy with soiling and megarectum unresponsive to any treatment since infancy. After CM, irritable bowel syndrome with constipation was identified and tegaserod was administered. The third case was an 8 years old boy with repaired anorectal malformation and permenant transverse colostomy. After evaluation of unused distal part of the colon, closure of the colostomy was advised to the parents. The fourth case was a six years old boy with difficulty of defecation since infancy and increasing narcolepsy. Abnormal propulsive activities were determined in his CM study and he was taken to the follow-up. The fifth case was a 5 years old boy with lymphoma and gradually increasing obstruction of the colon. There was not any propulsive activity during the CM study. This patient was thought as having paraneoplastic syndrome. The last case was a 17 years old girl with repaired cloacal malformation and transverse colostomy. Motility of distal colon was evaluated prior to colostomy closure and contractions like propagating spastic motor complex were observed. Conclusion: CM, in spite of its invasiveness, is a very useful study, especially in selected cases whose colonic motility cannot been evaluated by the other methods.