Akademik Veri Yönetim Sistemi
Annals of Medical Research, cilt.27, sa.8, ss.2022-2030, 2020 (Hakemli Dergi)
Aim: Gastric carcinoma is the fourth most common carcinoma worldwide. The relationships established between the tumormorphology and the prognosis have not been very effective until recent times. Poorly Differentiated Clusters (PDCs); are structuresthose can be easily identified in H&E sections. A new grading system based on PDC count has been studied in colorectal carcinoma;and found to be associated with prognosis. We have aimed to investigate this concept in gastric carcinoma.Material and Methods: Our study included 80 cases, consisting of 16 females and 64 males having gastric carcinoma with intestinalmorphology. For each case; conventional grade, PDC grade and prognostic parameters to be applied in the study were determined,and statistically compared.Results: Significant discrepancy was found between the two grading systems. PDC tumor grades were statistically related to; medianmetastatic lymph node counts, metastatic lymph node ratios, lymph node stages (pN) and the presence of perineural invasion.Conclusion: In stomach carcinoma; PDC grading system was found to be related to a significant part of the expected parametersand may have a prognostic value.