Correlation between intrahepatic hepatitis B virus cccDNA levels and other activity markers in patients with HBeAg-negative chronic hepatitis B infection


Guner R., Karahocagil M., Buyukberber M., Kandemir O., URAL O., USLUER G., ...Daha Fazla

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, cilt.23, sa.12, ss.1185-1191, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 23 Sayı: 12
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1097/meg.0b013e32834ba13a
  • Dergi Adı: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1185-1191
  • Anahtar Kelimeler: hepatitis B core antigen, hepatitis B early antigen-negative chronic hepatitis, hepatitis B surface antigen, hepatitis B virus, hepatitis B virus covalently closed circular DNA, immunohistochemistry, quantitative hepatitis B surface antigen, HBV DNA LEVELS, CLOSED CIRCULAR DNA, SURFACE-ANTIGEN, NATURAL-HISTORY, LIVER HISTOLOGY, HBSAG LEVELS, CORE, THERAPY, DECLINE, REPLICATION
  • Gazi Üniversitesi Adresli: Evet

Özet

Objective The aim of this study was to demonstrate the relation between intrahepatic (IH) hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) levels and the other HBV replicative intermediates and hepatocyte expression of HBV antigens.