EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY, cilt.51, sa.1, 2025 (SCI-Expanded, Scopus)
Purpose This study aimed to evaluate the prognostic value of the red cell distribution width (RDW) to albumin (RA) ratio in predicting in-hospital, three-month, and one-year mortality in elderly patients undergoing hemiarthroplasty for hip fractures. Methods This retrospective, single-center, observational study included patients aged 65 years and older who underwent hemiarthroplasty for a hip fracture between January 2018 and December 2023. Demographic data, laboratory parameters, and mortality outcomes (in-hospital, three-month, one-year) were analyzed. Logistic regression models were used to identify independent risk factors for mortality, and receiver operating characteristic curve analysis was performed to assess the predictive value of the RA ratio compared to RDW alone. Results A total of 532 patients were included. Of the patients, 212 (39.8%) died within one year. The RA ratio was significantly higher in non-survivors (p < 0.001). Multivariate logistic regression showed that the RA ratio was an independent risk factor for in-hospital (OR: 1.45, 95% CI: 1.13-1.87, p = 0.004), three-month (OR: 1.66, 95% CI: 1.34-2.06, p < 0.001), and one-year mortality (OR: 2.09, 95% CI: 1.66-2.63, p < 0.001). The AUC for RA was higher than RDW alone for in-hospital mortality (0.76 vs. 0.66, p = 0.004), three-month mortality (0.66 vs. 0.59, p = 0.007), and one-year mortality (0.68 vs. 0.61, p = 0.002). Conclusion The RA ratio is a significant predictor and independent risk factor for short- and long-term mortality in elderly hip fracture patients undergoing hemiarthroplasty. Given its superior prognostic value compared to RDW alone, the RA ratio may serve as a useful, readily available biomarker for early risk stratification in clinical practice.